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249 In the brains of transgenic parkin-deficient mice, the inhibition of p53 caused by parkin deficiency increases XBP-1 expression, which in turn promotes DJ-1 expression by binding and transactivating the DJ-1 gene promoter

(Fibroblast Growth Factor) may improve memory (19)

Individuals carrying genetic variants associated with chronic inflammation, impaired antioxidant defenses, or mitochondrial dysfunction may theoretically derive greater benefit from therapies that enhance endogenous repair pathways