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Effect of oral vitamin C supplementation on serum uric acid: A meta-analysis of randomized controlled trials

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It has been postulated that early-onset obesity carries favourable adipose distribution, conferring a metabolically healthier phenotype than if obesity develops in older adults [20]

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published in Annals of Internal Medicine a placebo-controlled study in 2009 that found that eszopiclone use in the first 14 nights of PAP initiation resulted in the use of PAP for 20.8% more nights compared to placebo [36, 38]