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Obesity is a clinical feature of PCOS that can exacerbate hormone disorders and clinical symptoms
Addressing lifetime metabolic disease and endometrial cancer risk is necessary for patients with polyendocrine metabolic ovarian syndrome (formerly polycystic ovary syndrome)
Patients taking insulin or sulfonylureas should monitor blood glucose more frequently and work with their healthcare provider to adjust these medications as needed to prevent hypoglycemia
For a drug to be approved for the pregnant population, it must go through rigorous testing with that population, and that has not yet happened for semaglutide or other GLP-1 (glucagon-like peptide 1) agonists, says Carrie Burns , MD, a board-certified endocrinologist and director of diabetes in pregnancy at Penn Medicine in Philadelphia
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Many patients taper off gradually while maintaining lifestyle changes
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