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However, this does not typically result in their death due to the capacity of Glu to synthesize glutathione (GSH), a vital antioxidant that plays a crucial role in cancer cells and their resistance to oxidative stress [45]
A population of regulatory CD8 + T cells may protect against plaque development by selectively killing immune cells that contribute to the overall inflammatory microenvironment
For example, though Ahr can inhibit CD4 + T cells function and support Tregs differentiation [142], it promotes the antimicrobial activity of macrophages and both CD8 + T cells and NK cells-mediated cytotoxicity [132, 135, 143,144,145]
Under this frame, it was observed that the association between lead exposure and ALS risk may correlate with particular GSTP1 gene polymorphisms 66
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Molecules (2022) 27:1620
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