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Week 1-4: 1mg weekly Week 5-8: 2mg weekly Week 9-12: 4mg weekly Week 13-16: 6mg weekly Week 17-20: 8mg weekly Week 21+: 12mg weekly (if tolerated) The Phase 3 TRIUMPH-4 trial used a slightly modified approach
BMI 30+ or BMI 27+ with comorbidities, lifestyle modification documentation
Receive a Prescription if Clinically Justified If your clinician decides tirzepatide is suitable, they can prescribe it or an appropriate alternative
It is possible that it could increase, decrease, or be unchanged
Options include dose adjustment within the weekly framework, compounded formulations offering flexible pricing, or a switch to a longer-acting GLP-1 variant under clinical investigation
With consistent lifestyle changes, improvements can begin within a few weeks, but significant metabolic restoration may take a few months depending on the individual.
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