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Dehydration and volume depletion, for example, due to vomiting and diarrhea, can increase this risk
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It is unclear if the increased risk of NAION is specific to semaglutide or also true of other GLP-1 receptor agonist drugs, the study authors wrote in their paper
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3d and 3f, g), which might result in progressively greater loss of cell surface receptors over time, despite similar acute endocytosis rates
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