Both groups also made lifestyle changes like reducing their diet by 500 calories and exercising for 150 minutes per week
The assessed variables were total prostate-specific antigen, prostate volume, peak systolic velocity, end-diastolic velocity, resistive index of cavernosal penile arteries, nocturnal penile tumescence, total and free testosterone, prolactin, luteinizing hormone, International Index of Erectile Function score, Depression Melancholia Scale score, fatigue scale score, and incidence of side effects
Early responders who lost at least 15 percent of their body weight by week 24 went on to achieve an incredible 27.7 percent mean weight loss by week 72 (Source: STEP UP Trial, Dicker et al., ECO Abstract 2026)
The starting dose is usually low and then increased gradually
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Understanding how they compare to other options helps you make informed decisions about your protocol