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Vitamin B12 and Folate July 16, 2026 Key points Vitamin B12 and folate are vitamins that serve important functions in the human body

As a cofactor, cobalamins are essential for two cellular reactions: the mitochondrial methylmalonyl-CoA mutase conversion of methylmalonic acid (MMA) to succinate, which links lipid and carbohydrate metabolism, and the activation of methionine synthase, which is the rate-limiting step in the synthesis of methionine from homocysteine and 5-methyltetrahydrofolate

To view a copy of this licence, visit About this article Cite this article Pakchotanon, K., Kanjanasuphak, N., Chuasuwan, A