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Kidney and cardiovascular effectiveness of SGLT2 inhibitors vs GLP-1 receptor agonists in type 2 diabetes

The STEP 8 clinical trials found that once-weekly semaglutide 2.4 mg led to significantly greater weight loss than once-daily liraglutide 3.0 mg at 68 weeks in overweight adults without diabetes

All raw data were formatted to net CDF via Chemstation (Agilent)

Advanced dendritic glucan-derived biomaterials: from molecular structure to versatile applications

But when the body cant produce enough insulin or use it normally, glucose accumulates in the blood and leads to diabetes.8 People with diabetes need to carefully manage their blood sugar, and the insulin-stimulating action of a GLP-1 peptide helps them to do that

Note on Phase 3 sources: Topline results for TRIUMPH-4 (announced December 2025) and TRANSCEND-T2D-1 (announced March 2026) are sourced from Eli Lillys primary disclosures