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Reduced glucose levels can also increase the production of ROS causing oxidation damage and interfere with signaling pathways and finally lead to apoptosis and necrosis [16] (Fig

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Specifically, safflower oil containing only the 0.7% level of CLA had no effect on overall BMI or total adipose mass, but it did lower glucose and trunk fat levels as well as increase lean muscle mass levels, while CLA lowered overall BMI and total adipose mass

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