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When deficiency is suspected based on clinical features (fatigue, paraesthesia, cognitive changes) or risk factors (vegan diet, gastric surgery, certain medications), serum B12 measurement guides appropriate intervention

The research team also conducted a double-blind, cross-over study involving eight healthy men (average age, 36 years) who received either glutathione or placebo for two weeks

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doi: 10.1038/bjc.1987.223 75 YoonHLeeS