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In a head-to-head trial of comparable dose levels, participants using tirzepatide (Zepbound) experienced an average weight loss of 20.2%, while those on semaglutide (Wegovy) achieved a 13.7% reduction
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The appetite suppression caused by tirzepatide can make it challenging to meet protein and micronutrient requirements, which is especially problematic for conditions where malnutrition worsens disease outcomes
Tirzepatide isnt recommended during pregnancy because theres not enough human research to confirm its safe for a developing fetus
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"It is up to you to make the lifestyle changes for long-term results." McConnell advised other GLP-1 patients to have a plan for how to maintain their healthy lifestyles, including eating well and getting exercise, once theyve stopped taking these medications
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