b12 intramuscular injection dosage contraindications to injections of Vitamin B12 Monthly Dose: Typical Dosages & Administration Methods Oral vs. Vitamin B12 – Vitamin B12 Injections: 8 Dosage

As a cofactor, cobalamins are essential for two cellular reactions: the mitochondrial methylmalonyl-CoA mutase conversion of methylmalonic acid (MMA) to succinate, which links lipid and carbohydrate metabolism, and the activation of methionine synthase, which is the rate-limiting step in the synthesis of methionine from homocysteine and 5-methyltetrahydrofolate

doi:10.3109/15563659309000395

Naurath, H

People who have had allergic reactions to cobalt or cobalamin (the form of B12 in injections) should avoid them

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But, we need more studies to know how well it works and the best dose