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A previous drug repurposing screen found statins, which act on HMG-CoA reductase (HMGCR) to be a reliable host target for reducing Cryptosporidium growth in vitro 18 , so it was encouraging to see HMGCR coming up as a hit in our screen
By blunting the GH pulse from CJC 1295/Ipamorelin, youre directly reducing the protocols effectiveness for lipolysis (fat breakdown)
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doi: 10.3389/fphar.2023.1271321 33 SholevarCLiuNMukarramaTKimJLawrenceJCanterR
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