Preclinical studies have observed its modulatory effects on corticotropin and somatostatin secretion, suggesting its role in neuropeptide feedback loops relevant to stress adaptation and hormonal rhythms
Potential role of stem-cell chemokines in type 2 diabetes Experimentally, potentiation of SDF-1 can act to promote pancreatic -cell genesis, differentiation and survival, and the chemokine may protect cells from destruction as diabetes progresses [12, 13]
It also acts like an antioxidant
doi:10.1172/JCI106182
While the recent phase 3 trial for orforglipron was specifically for type 2 diabetes and not weight loss, the study found that patients who took the drug lost considerable weight
As the only injection to support weight loss in three ways, Eli Lilly, same manufacters of Mounjaro has developed Retatrutide, a new weight loss medicine