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To discharge an unacceptable increase in cardiovascular risk, the upper bound of the CI of the MACE-4 HR comparing pooled tirzepatide and pooled comparator less than 1.8 should be demonstrated

The Rat Brain in Stereotaxic Coordinates (Academic Press, 2013)

Weeks 1-4: 2mg weekly injection Weeks 5-8: 4mg weekly injection Weeks 9-12: 8mg weekly injection Injection day: Sunday evenings Daily protein target: 90-100g minimum Water intake: 80+ ounces daily At the 3-month mark I feel like a different person