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The safety profile is strong: toxic doses sit roughly 300 to 3,750 times higher than recommended therapeutic amounts, and injection site irritation remains the most commonly reported side effect

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doi: 10.1016/j.cmet.2021.11.010 18 BalmerMLMaEHThompsonAJEppleRUnterstabGLtscherJet al

Since branded semaglutide and tirzepatide are now fully available, prescribers are expected to document that the compounded version serves a specific individualized medical need that the branded version cannot