The problem is that most resources either dismiss side effects entirely or exaggerate them into something terrifying
When Combination Therapy May Be Considered Dual GLP-1 and DPP-4 therapy is typically considered when monotherapy with either agent achieves insufficient glycemic control
5 Neuroprotective action It protects nerve cells from oxidative stress and promotes the regeneration of damaged neural pathways, making it especially effective for neuropathic and inflammatory pain such as sciatica
Geroscience 42 , 667686 (2020)
And it means improved hormone regulation, since growth hormone, which is critical for body composition, is released primarily during deep sleep
Baseline characteristics were broadly similar across the treatment groups, although body weight and BMI were slightly higher in the placebo-treated patients and HbA1c was higher in those receiving tirzepatide 2.510.0 mg than in the other groups