Every client receives clear instructions included with their medication for safe, at-home self-administration
Your doctor will conduct a comprehensive clinical assessment including: Detailed medication and supplement history , including over-the-counter vitamins and injections Review of symptoms suggesting liver, kidney, or haematological disease Physical examination for hepatomegaly, splenomegaly, jaundice, or lymphadenopathy Additional blood tests , such as full blood count, liver function tests, renal function, and inflammatory markers Depending on initial findings, further investigations may include: Liver ultrasound or imaging if hepatic pathology is suspected Haematology referral for blood film examination, bone marrow biopsy, or specific tests for myeloproliferative disorders Measurement of holotranscobalamin or methylmalonic acid if functional B12 status needs clarification despite high total B12 Targeted investigations based on clinical findings and following NICE guidance for suspected serious conditions Treatment focuses on addressing the underlying cause rather than the elevated B12 itself
Choice depends on the patients goals and health profile
Medical Journal of Australia , 199: S27-S32
Vitamin B12, a water-soluble nutrient, is integral to the overall health of your nerve cells, the generation of DNA, and the production of red blood cells
This guide covers how each delivery method works, the core clinical differences between them, who benefits most from each option, and what to expect regarding side effects, treatment frequency, and cost
