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Published: June 10, 2010 Copyright: 2010 Schrettl et al

Patients with chronic kidney disease, cardiovascular diseases, and those with obesity related complications such as moderate to severe obstructive sleep apnea (OSA) should not use microdoses of GLP-1 medications

Circulating alpha-klotho is related to plasma aldosterone and its follow-up change predicts CKD progression

All numbers were similar between the 10 and 20 mg oral dose, except for treatment discontinuation, which was 12% for the lower dosage