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The first of a series of CVOT was the ELIXA trial, which compared patients with T2D and a history of a heart attack or unstable angina to either receive once daily injections of lixisenatide or placebo
The dual targeting of GLP-1/GLP-2 and GIP receptors is hypothesized to enhance satiety, regulate glucose metabolism, and support tissue repair in metabolic disorders
In strongyloidiasis, IgG, IgM, and IgE responses to parasite antigens are implicated in disease protection [119, 132]
Expert consensus document
However, these proposed benefits are based on theory and limited research rather than established clinical evidence
IL-10 deficiency reveals a role for TLR2-dependent bystander activation of T cells in Lyme arthritis
