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The 12mg weekly arm produced a 24.2% mean body weight reduction over 48 weeks, with 26% of participants achieving at least 30% total body weight loss a threshold previously unattained by any pharmacological intervention in a clinical trial setting

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DADS were identified to have diminished inflammation, oxidative stress and DNA lesions on the bladder over the topics of pro-inflammation cytokines regulation and also the MAPKs signaling pathways (Anwar et al., 2020)