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doi:10.1101/2023.11.16.567423 15
GLP-1 receptor agonists (like semaglutide and liraglutide) mimic this signal pharmacologically
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Aronne notes that tirzepatide in Zepbound and Mounjaro works on GLP-1 plus an extra hormone called GIP, making it more potent than the semaglutide in Wegovy and Ozempic
The intensity does not need to be extreme
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