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However, landmark analysis, adjusting the cohort selection period to 2, 6, 9, and 12 months post-transplant, demonstrated consistent beneficial effects of GLP-1 RAs on all-cause mortality, MACEs, and MAKEs (Supplemental Table 13)

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The mechanisms proposed for this protective effect include modulation of inflammatory pathways, reduction of oxidative stress, and improvement of metabolic parameters that contribute to liver carcinogenesis (Arvanitakis et al., 2022)