Our findings highlight the potential for clinical use of Cbi-Ex4 for millions of patients seeking improved glycemic control without common side effects (e.g., emesis) characteristic of current GLP-1 therapeutics.
This means it's a synthetic chemical compound small enough to be absorbed directly through the gut wall
Researchers suspected that this same mechanism could help with addiction cravings for substances ranging from alcohol to cocaine to opioids
It is reasonable to say Ozempic may affect the gut microbiome indirectly, but it is not accurate to claim that it is proven to fix the microbiome or that microbiome changes alone explain all outcomes
By the end of the study, people taking the extract saw small but measurable changes in body fat and weight compared with the placebo group
It is the job of the L cells to secrete GLP-1s and PYY to stimulate insulin secretion from the pancreatic beta cells, inhibit glucagon release, and slow gastric emptying after a meal