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In a performance comparison between propanephosphonic acid anhydride and other peptide coupling reagents for the preparation of a nonapeptide drug, it was found that this reagent was superior to other reagents with regards to yield and low epimerization

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Even modern biologics have a low-to-moderate response rate

This blunting of the microglial response attenuated reactivity to LPS and, furthermore, altered behavior in mice, where exposed mice showed an inability to react appropriately to psychosocial stress (Lee et al., 2022)