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Intramuscular (IM) B12 injections using hydroxocobalamin, the preferred licensed form in the UK are recommended when: Oral supplementation has failed to correct a documented deficiency The patient has difficulty adhering to daily oral regimens Serum B12 levels remain persistently low despite adequate oral dosing There is clinical evidence of neurological or haematological complications In line with BNF guidance, the standard IM regimen for confirmed deficiency without neurological involvement is a loading course of 1 mg hydroxocobalamin on alternate days for two weeks , followed by maintenance of 1 mg every three months
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Subcutaneous (SubQ) Needles Subcutaneous needles are suitable for injections into the fatty tissue just beneath the skin
Handle in accordance with applicable laboratory safety guidelines
doi:10.1159/000053183 Heffernan M, Summers RJ, Thorburn A, et al
Q: What precautions should be taken before and during the treatment process
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