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Different patient populations, different trial designs, different enrollment criteria, and different measurement protocols all introduce noise that makes precise numerical comparisons between CagriSema and tirzepatide unreliable

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Research published in the Journal of Clinical Investigation found that GLP-1 signaling influences both REM and non-REM sleep stages through hypothalamic pathways

392 :e086886 doi:10.1136/bmj-2025-086886 Vlker KM, Prechtl BLH, Bormann NL, Choi DS