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In the SURMOUNT-1 trial the landmark study of Zepbound in adults without diabetes participants lost an average of: 15% of body weight on 5 mg (~34 lbs) 19.5% of body weight on 10 mg (~44 lbs) 20.9% of body weight on 15 mg (~48 lbs) 3.1% on placebo (with diet and exercise) At the highest dose, 91% of participants achieved weight loss of 5% or more which is the threshold at which meaningful health benefits begin
Can it Support Weight Loss
1999 [cited 2025 Apr 2];10(11):242639
Proper site selection and systematic rotation between these areas help prevent tissue changes that can impair medication absorption and ensure consistent therapeutic outcomes
Most reputable telehealth platforms begin with an intake quiz or a health assessment, and the free assessment quiz is the natural starting point
For context on how these numbers compare to other dose levels, our tirzepatide dosage chart in units covers every dose from 2.5 mg through 15 mg
