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One study in diet-induced obese mice found that an NNMT inhibitor combined with a calorie-restricted diet was associated with shifts in gut bacterial populations, suggesting metabolic intervention can have knock-on effects on gut composition
[PMID: 6280867] PubMed record related to this compound for laboratory literature review
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Thus, in both folate and vitamin B 12 deficiencies, folate is unavailable to participate in DNA synthesis
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