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Efficacy and safety of taspoglutide monotherapy in drug-naive type 2 diabetic patients after 24 weeks of treatment: results of a randomized, double-blind, placebo-controlled phase 3 study (T-emerge 1)
Applicable Equation Assuming a drug is completely absorbed from the gastrointestinal tract (i.e., the fraction absorbed, f a , is 1), its oral bioavailability (F) is determined entirely by the fraction that escapes hepatic extraction
Regulation of PI3K signaling in cancer metabolism and PI3K-targeting therapy
Even if small amounts transfer, infant digestive enzymes would break down the molecule before absorption
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