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Results: The CLP-induced SAE model showed significant hippocampal damage, microglial activation, cognitive deficits, and increased levels of pro-inflammatory cytokines, ROS, and MDA
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10.1002/pros.22869 Prostate 67 JankovicJ
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Notice that GSH goes up for low estradiol values, reaches a peak and descends for high estradiol values Variation of GSH steady state depending on S In our model, we take the activation of GCL and GPX by estradiol to be 80%, which is a reasonable choice supported by the experimental and clinical data discussed above
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