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It is a huge hurdle we and others in the B12 community are working on to overcome
Damage to nerve tissue (peripheral neuropathy), leading to pain, numbness, and weakness in extremities: These can be caused by the vitamins role in the proper functioning of the nervous system
BioMed research international , 2021 , 9924314
Study participants receiving active treatment saw three times the weight loss experienced by those in the placebo group
Reference: Nicotinamide N-Methyltransferase in Cardiovascular Diseases: Metabolic Regulator and Emerging Therapeutic Target (2025)
Four hundred and thirty (88%) of these patients have conditions for which the drug is a proven benefit , so the increased frequency of injections accounts for most of the observed excess
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