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After first use, most compounded vials remain stable for 28 days in the refrigerator, though some pharmacies with rigorous stability testing issue longer beyond-use dates of up to 90 or even 120 days

Initially, all unopened semaglutide injection pens absolutely require refrigeration

B12 deficiency can mimic GLP-1 side effects like fatigue and brain fog, making it difficult to distinguish medication effects from nutritional deficiency without testing

For personalised advice, the NHS offers resources to support safe and effective health management

The New England Journal of Medicine , 384 (11), 989-1002