The compound's ability to restore tissue homeostasis and reverse age-related functional decline in animal models provides direct evidence for the role of senescent cells in aging processes, while its applications in cancer research offer insights into senescence mechanisms in disease progression and administration resistance
Mesenchymal stem cell therapy can reduce serum amylase and TNF- concentrations, increase serum IL-10 concentrations, reduce brain microvascular endothelial cell apoptosis, up-regulate claudin-5 levels, and reduce MMP-9 levels [57, 68]
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