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However, their clinical translation is often impeded by inherent challenges such as poor bioavailability, limited aqueous solubility, and rapid systemic clearance, which collectively hinder their effective delivery to targeted ocular tissues [347]
Postuma RB, Berg D, Stern M, Poewe W, Olanow CW, Oertel W, et al
In affective disorders such as depression, BD, and PTSD, alterations in serotonergic, dopaminergic, and GABAergic signaling often regulated by microbial misbalanced signaling render gut microbiome as strongly connected to emotional and behavioral aptness
Perkins ND, Gilmore TD (2006) Good cop, bad cop: the different faces of NF-B
Histone h3 glutathionylation in proliferating mammalian cells destabilizes nucleosomal structure
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