In animal studies, GLP-1 agonists were excreted in breast milk
An August study published in the Journal of the American Medical Association (JAMA) found that people who took semaglutide drugs like Wegovy have double the chance of developing NAION as people who did not take such drugs
doi: 10.1001/jama.2021.1831 103 CowartK
UFE may be a way to treat fibroids instead of: A hysterectomy (HIS-the-REK-toh-mee), which is a surgery to remove the uterus
Thus, acting in diverse terminal fields, dopamine confers motivational salience ("wanting") on the reward itself or associated cues (nucleus accumbens shell region), updates the value placed on different goals in light of this new experience (orbital prefrontal cortex), helps consolidate multiple forms of memory (amygdala and hippocampus), and encodes new motor programs that will facilitate obtaining this reward in the future (nucleus accumbens core region and dorsal striatum)
STEP-HFpEF Trial (NEJM, 2023): 13.3% weight loss plus major improvements in HFpEF symptoms and function