Patients often notice increased strength, better recovery, and gradual improvements in muscle density alongside fat reduction
Administration: Typically taken as a once-weekly injection under the skin
Dysesthesia: Retatrutide's Unique Side Effect Dysesthesia abnormal skin sensations including tingling, numbness, or unusual touch sensitivity is not reported with tirzepatide or semaglutide
Data was self-reported by 1,671 surveyed customers who checked in with their provider between their first and third check-in between 4/7/22 and 2/9/26
Food and Drug Administration recently issued a warning against using unapproved GLP-1 drugs for weight loss, citing quality concerns, false or misleading labels, counterfeit drugs and more than 1,600 reports of adverse effects associated with compounded GLP-1 medications
Y.KeremuB.et al (2025a)