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Investigations assess cytokine-expression profiles, epithelial-barrier integrity, mucosal architecture, tight-junction organization, and tissue-remodeling responses following experimental enteral delivery
While the serum concentration of cobalamin is used diagnostically, the reactions catalyzed by cobalamin dependent enzymes occur in the mitochondria, making it difficult to assess the state of cobalamin availability in the patient
doi: 10.1016/j.smim.2016.10.009 34 ONeillLAKishtonRJRathmellJ