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GLP-1 nausea is usually worst during dose escalation and improves with time
1 The most common side effects affected the gut, as with other GLP-1 medications
Fat slows gastric emptying further, compounding the effect tirzepatide already has
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Future directions include the need for well-designed RCTs with large sample sizes to confirm findings, assessment of long-term safety and tolerability in patients with HS, and further research into the molecular mechanisms by which GLP-1 RAs affect HS pathophysiology
Its approximately 24-hour half-life supports once-daily administration, making it convenient for sustained study protocols
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