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Options for managing tolerance include a brief dose reduction for 4 to 8 weeks ("drug holiday" at a lower dose, not complete cessation), lifestyle optimization to maximize the medication effect, evaluation for other contributing factors (thyroid function, cortisol, sleep quality, medication interactions), and consideration of adding a complementary compound to address specific aspects of the plateau

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The underlying cause of deficiency is the most important determinant

Vitamin B12 plays an indispensable role in several vital biological processes: Nervous System: It is essential for the synthesis of myelin, the protective sheath around nerve fibres

What changes is the added B12 support and, in some cases, the overall experience

B12 injections are elective wellness services