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In the discovery of therapeutic drugs, the effects of well-established autophagy regulatory agents like metformin and rapamycin are explored
Quercetin Ameliorates Paclitaxel-Induced Neuropathic Pain by Stabilizing Mast Cells, and Subsequently Blocking PKC-Dependent Activation of TRPV1. Acta Pharmacologica Sinica, vol
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GLP-1RAs have pleiotropic effects: they improve neurogenesis, reduce apoptosis, protect neurons from oxidative stress, and reduce neuroinflammation in various neurological conditions, and it is these beneficial effects that can be used in aging-related diseases, mainly AD and PD
248,251,252 This mechanism is particularly evident in the use of GLP-1-based drugs, such as GLP-1RAs, in the treatment of T2DM
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