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To stop self-aggregation, these chaperones tend to bind to the hydrophobic portion(s) of the partially folded proteins
doi: 10.1007/s00125-011-2232-3 188 WellenKEHotamisligilGS
Speakman JR
Glucose metabolic gene expression in growth hormone transgenic coho salmon
Whilst the pathogenesis of PD remains unclear, impaired insulin signaling appears detrimental in the development and progression of PD-related neurodegeneration
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