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We selected the key genes associated with MAFLD and subsequently performed GO (Gene Ontology) and KEGG (Kyoto Encyclopedia of Genes and Genomes) analyses to explore the enriched biological processes and signaling pathways

Major Ingredients Water, Centella Asiatica Extract (25.3%), Glycerin, Cetyl Ethylhexanoate, Butylene Glycol, Polyglyceryl-3 Methylglucose Distearate, Niacinamide (20,000ppm), Beeswax, Stearic Acid, Sodium Polyacryloyldimethyl Taurate, Silica, Sodium Hyaluronate, Glyceryl Stearate, Butyrospermum Parkii (Shea) Butter, Macadamia Ternifolia Seed Oil, Hydrogenated Polydecene, Betaine, Glutathione (1,000ppm), Trehalose, Adenosine, Citric Acid, Trideceth-10, Disodium EDTA, Sodium Citrate, Nelumbo Nucifera Extract, Artemisia Annua Extract, Oryza Sativa (Rice) Extract, Saccharomyces Ferment, Solanum Melongena (Eggplant) Fruit Extract, Melaleuca Alternifolia (Tea Tree) Leaf Extract, Hydrolyzed Collagen, Caprylic/Capric Triglyceride, Hydrogenated Lecithin, Xanthan Gum, Carbomer, Arginine, Squalane, Beta-Glucan, Dipropylene Glycol, Hippophae Rhamnoides Fruit Extract, Madecassic Acid, Asiaticoside, Asiatic Acid, Propanediol, Hydroxyacetophenone, 1,2-Hexanediol, Ethylhexylglycerin, Dipotassium Glycyrrhizate Ingredients subject to change at manufacturer's discretion

Samples were resuspended in 160 L EPPS buffer (200 mM, pH 8.0) using a probe sonicator (1 1015 pulses, power output 20%) and then digested with LysC (4 L of 0.5 g/L per sample, resuspended in HPLC grade water, Wako-chemicals, Fujifilm #125-05061) for 2 h at 37 C in a shaker incubator

Handog EB, Datuin MS, Singzon IA

[1] Benzyl alcohol acts as a bacteriostatic agent, meaning it inhibits the growth of bacteria in the solution

Theories for this rise in early-onset CRC (under age 50) point to a mix of lifestyle and environmental factors