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In laboratory and animal studies, GHK-Cu is reported to stimulate collagen and elastin synthesis , support wound healing and angiogenesis , act as an antioxidant and anti-inflammatory , and modulate the expression of genes tied to skin repair and tissue remodeling [3] [4] [5]

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[1] [3] A family of histone deacetylases known as sirtuins (Sirt 1-7) controls a number of proteins involved in cellular metabolism, stress responses, circadian rhythms, and endocrine functions

Redox Signal 36 , 220243 (2022)

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An MTHFR variant does not reliably predict whether methylfolate will be beneficial or poorly tolerated