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[30] This reaction is under review for use as a catalyst for chemical dehalogenation, organic reagent and photosensitized catalyst systems

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Exemplifying this, efgartigimod is in phase II clinical trials for the treatment of post-COVID-19 postural orthostatic tachycardia syndrome (NCT05918978, NCT05633407)

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While hydroxocobalamin is not already methylated, it is readily converted to this form to support the methylation cycle