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Therefore, studies have investigated how CHAC1 is regulated in tumor cells and their microenvironment: Prostate cancer patients frequently develop resistance to docetaxel, a challenge in which cancer-associated fibroblasts (CAFs) have been shown to play a significant role through exosome-mediated signaling (Zhao et al
Supports wound healing and cellular regeneration
In innate immunity, ER-mitochondria contact dynamics are intricately linked to macrophage polarization and inflammatory thresholds
Using siRNA to knockdown NADPH oxidase (NOX), it was demonstrated that gomisin L1 increased intracellular ROS levels and promoted apoptosis in ovarian cancer cells through NOX (81)
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