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Shults CW, Haas RH, Passov D, Beal MF

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[86] found that semaglutide, as a GLP-1 analog, can directly act on fat cells, increase the expression of thermogenic genes for browning phenotype maintenance, improve the expression of UCP1, mitochondrial biosynthesis and thermogenic marker, thereby contributing to weight loss

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Then Weston isolated and identified three v-MYB related genes in vertebrates, namely c - MYB , A - MYB and B - MYB , which were confirmed to regulate cell proliferation, tissue differentiation and cell death (Weston, 1998)