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Ozempic as an add-on to basal insulin and Ozempic 1 mg vs 2 mg Primary endpoint: change in A1C from baseline SUSTAIN 5: add-on basal insulin 1,10,11 In adult patients with type 2 diabetes on basal insulin metformin Mean change in A1C from baseline at Week 30 Mean baseline A1C: SUSTAIN FORTE: Ozempic 1 mg vs 2 mg 1,8 In patients with type 2 diabetes on metformin sulfonylurea Mean change in A1C from baseline at Week 40 Mean baseline A1C: Results for SUSTAIN 5 and SUSTAIN FORTE based on sensitivity analyses of retrieved dropout population

Long-Acting or PEGylated Peptides: Up to Several Weeks Modified peptides such as CJC-1295 with DAC or PEG-MGF have long biological half-lives and extended detection windows

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Liraglutide slows down and sometimes even inhibits tumor growth of cancers in mice in in vivo studies

Candeias E, Sebastio I, Cardoso S, Carvalho C, Santos MS, Oliveira CR, et al

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