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Semaglutide and traditional cholesterol medications such as statins, ezetimibe, and PCSK9 inhibitors work through fundamentally different mechanisms and should not be viewed as interchangeable therapies

Expected weight loss by starting weight Based on SURMOUNT-1 data showing 15 to 21% body weight reduction over 72 weeks: Starting at 200 pounds: Expected loss of 30 to 42 pounds over 72 weeks (ending at 158 to 170 pounds)

Immunoblots show SUMM2 using -HA antibodies (top panel), and TPR14 TPR or TPR5G using -FLAG antibodies (middle panel) with CBB staining of RBC as the loading control (bottom panel)

The aches and pains in my back and all my joints, from all of the excess weight I was carrying, have disappeared

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